High Purity 99.9% High Quality Melanotan II CAS: 121062-08-6 in Stock

Model NO.
CAS: 121062-08-6
Colour
White
Transport Package
10vials/Kit
Specification
10mg/Vials
Trademark
Mirun
Origin
Shanghai
Production Capacity
500kg/Day
Reference Price
$ 1.80 - 5.40
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Product Description

Product Description
 
Melanotan II Basic information
Description   Historical Development   Uses   BENEFITS OF A MELANOTAN II   SIDE EFFECTS   Controversy   Dosage
Product Name: Melanotan II
Synonyms: Acetyl-(Nle4,Asp5,D-Phe7,Lys10)-cyclo-α-MSH (4-10) aMide Melanotan II, MTII, ;MelanotanII Acetate(MT-2);AC-NLE-CYCLO(-BETA-ASP-HIS-D-PHE-ARG-TRP-EPSILON-LYS-NH2);AC-NLE-CYCLO[(BETA-D)-HFRW-(EPSILON-K)]-NH2;AC-NLE-CYCLO(-ASP-HIS-D-PHE-ARG-TRP-LYS-NH2) ACETATE SALT;AC-NLE4-C[ASP5, D-PHE7, LYS10]ALPHA-MSH (4-10)-NH2;AC-[NLE4, ASP5, D-PHE7, LYS10]-ALPHA-MSH (4-10)-NH2;(AC-NLE4, ASP5, DPHE7, LYS10)-CYCLO-ALPHA-MSH (4-10) AMIDE
CAS: 121062-08-6
MF: C50H69N15O9
MW: 1024.18
EINECS: 1308068-626-2
Product Categories: Peptides ; Amino Acid Derivatives ; Peptide ; Melanocortin receptor ; 121062-08-6
Mol File: 121062-08-6.mol
 
 
Melanotan II Chemical Properties
density  1.43
RTECS  OL4225000
storage temp.  Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility  H 2 O: 5 mg/mL, soluble
pka 13.00±0.70(Predicted)
form  solid
color  white
InChIKey JDKLPDJLXHXHNV-MFVUMRCOSA-N
CAS DataBase Reference 121062-08-6(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
HS Code  3504009000
 
MSDS Information
 
 
Melanotan II Usage And Synthesis
Description Melanotan II is a synthetic analogue of the melanocortin peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that occurs naturally. In usage, Melanotan II has been revealed to have aphrodisiac and melanogenesis (tanning) effects that have been subjected to clinical trials and preliminary studies. The compound is a cyclic lactam analogue of α-MSH that has an amino sequence named MTII (Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2). Notably, no government drug regulatory agency across the world had approved for the use of any compound incorporating the Melanotan II peptide by 2010
Historical Development Melanotan II was first developed at the University of Arizona. Various studies conducted at the institution confirmed that the best defence against skin cancer was melanin activated in the skin, a tan. The researchers assumed that an effective procedure to reduce the rates of skin cancer in individuals would be by inducing the body's natural pigmentary system to produce a tan that would be protective before exposure to UV. Melanogenesis is a process by which the skin's pigment cells (melanocytes) produce the hormone α-MSH naturally causes the skin's pigment (melanin).
After numerous clinical trials by administration of the endogenous hormone to the body, the scientists found that though it appeared to work, α-MSH had a very short half-life in the body to be practical as a therapeutic drug. Therefore, they opted to look for a more stable and potent alternative that would be more practical. Subsequently, after numerous trials, they developed Melanotan I and after that Melanotan II.
Uses Malanotan II is used for tanning of the skin and producing of erections in men with erectile dysfunction when administered as a shot under the skin. Malanotan II is safe when used under strict medical supervision for treating erectile dysfunction. However, it may cause stomach cramps, tiredness, nausea, spontaneous erections of the penis, and darkened skin.
BENEFITS OF A MELANOTAN II Darker tan with less exposure to UV radiation
Tanning without sunburn, even for fair-skinned individuals
Possible reduction in the risk of Melanoma (skin cancer)
Possible reduction in the incidence of sun-damaged skin
Possible reduction in body fat
No sunburn, n tan lines
No sunless tanning streaks or fake tan removal
Possible increase libido
During clinical trials for its use as a tanning agent, melanotan II was found to be a potent stimulator of male erections. It has also been shown to increase female sexual desire in patients with sexual arousal disorder).
SIDE EFFECTS Short term side effects after administration include:
Facial flushing
Reduced appetite, nausea and vomiting
In males, spontaneous erections 1-5 hours after administration (priapism), associated with yawning and stretching complex
Long term, there is concern that melanotan II may increase the risk of:
Melanoma - a potentially serious form of skin cancer
Deepening of the color of moles, new moles and atypical melanocytic naevi
Melanonychia - brown to black discoloration of one or more nails
Suggested usage: daily for 1 - 2 weeks then one to two times weekly for maintenance.
Controversy Melanotan II is widely sold online and in beauty salons as well as gyms as melanotan in their marketing. These products purport to contain the same chemical composition as afamelanotide. These products have been declared illegal and do not have the same chemical components as Melanotan II. As such, countries issues warnings against their use.
Dosage Melanotan 2 has a half life of ~33 hours, this allows you to be very flexible with dosing. Recommended dosages start at 250mcg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.
If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 500mcg. 500mcg is the most common dosage amount administed by users. You can increase the dose as far as about 1mg but any higher is generally not advised and the users dosing 1mg/dose normally weigh around the 100kg mark.
Uses Melanotan II acetate salt has been used to study its inhibitory effects on feeding and energy expenditure in rats.
Uses Melanotan II Acetic Acid Salt, is a lab-made chemical that is similar to a hormone found in people. Melanotan II has been shown to have melanogenesis (tanning) and aphrodisiac effects on humans.
General Description Melanotan II induces melanogenesis and thus increases skin pigmentation. It is an analog of α-melanocyte stimulating hormone.
Biochem/physiol Actions Melanotan II is a MC3-R/MC4-R melanocortin agonist.
Clinical Use Melanotan II has been a new treatment for rosacea discussed in the various rosacea support groups on the internet.
Melanotan I and Melanotan II are both analogs of the peptide hormone alpha-melanocyte stimulating hormone (a-MSH) that tend to induce skin tanning. Melanotan II has the additional effect of increasing libido.
Melanotan II is an α-MSH analog which underwent clinical trials for the treatment of erectile dysfunction. Preliminary double-blind, placebo-controlled studies demonstrated the efficacy of melanotan in inducing penile erection in men with erectile dysfunction, although in a very restricted population.Unfortunately, there are no experimental data on the mode of action of melanotan II, as melanotan II is the first α-MSH agonist inducing penile erection when injected peripherally.
Illustration of the proerectile effect of melanotan II (MT-II) in humans. Placebo (A) or MT-II (B, 25 ug/kg and C, 133 ug/kg) was injected subcutaneously in patients and RigiScan recording was performed from 6 h. Apparent erections developed in 8 of 10 men treated with MT-II. (Reproduced with permission from Wessells H et al. Effect of an alphamelanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction. Urology 2000; 56:641-646.)
Side effects When given as a shot: Melanotan is POSSIBLY UNSAFE when given as a shot. It can causes nausea, stomachcramps, decreased appetite, flushing, tiredness, yawning, darkened skin, spontaneous erections of the penis, and other side effects. In some people, especially those with light skin, a change in the shape of moles, new moles, and skin cancer, have all occurred in people using melanotan.
 
Melanotan II Preparation Products And Raw materials
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Detailed Photos

High Purity 99.9% High Quality Melanotan II CAS: 121062-08-6 in Stock

High Purity 99.9% High Quality Melanotan II CAS: 121062-08-6 in Stock
High Purity 99.9% High Quality Melanotan II CAS: 121062-08-6 in Stock
Packaging & Shipping

Packing Method:

For small samples quantity <1 kilograms , inside we use double resealable zip bags and outside with aluminium Foil
Bags. For medium quantity 1-25 kilograms, we pack them in double-layer plastic ziplock bags (inside) with aluminium foil bag(outside). Then packed in cartons or small drums as your requirement via FedEx/TNT/DHL or special channal.
For larger quantity >25 kilograms, normally we pack them in drums(normally 25KG per) with two strong PET bags.
We do supply smaller packages like 10gram/50gram per bag as your requirement. Please contact us for more details if you have any question!
High Purity 99.9% High Quality Melanotan II CAS: 121062-08-6 in Stock

High Purity 99.9% High Quality Melanotan II CAS: 121062-08-6 in Stock Shipping Transit could be DHL.UPSTNT EMS Fedex and so on. For mass orders,it will be delivered by air or sea. Depending on your location,please allow 1-5 business days for your order to arrive. For small order please expect 3-7 days by UPS DHL EMS, For mass order,please allow 5-8 days by Air15-30 days by Sea.
 

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Company Profile

High Purity 99.9% High Quality Melanotan II CAS: 121062-08-6 in Stock

Hebei Mirun Import and Export Trading Co., LTD
Hebei Mirun Import and Export Trading Co., LTD is a company mainly engaged in high quality organic intermediates and other related
products research and development and sales for the integration of high-tech enterprises. Analysis of testing equipment, our
company has advanced and complete supporting system, formed the advanced chemical synthesis can quickly meet the applicable test
to the industrialized production of personalized requirements and seriation. If you are looking for a reliable supplier,we are the
perfect choice. We are a factory located in China. Provide door to door service. We have our own shipping that are very
professional in custom clearance, you need't to do anything.
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Q1:Are you trading company or manufacturer?
A1:We are chemical factory in China,So we can provide wholesale price.

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A2:We can provide you free sample for our existing products, the lead time is about 1-2 days. You just need to pay the sample delivery cost.

Q3:If the inspection result can not meet the agreement between the two sides, can you bear all the losses caused by this?
A3:Yes, we can. We guarantee that the samples provided will meet the needs of our clients and we will bear the risk of default.

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A4:Generally it is with 5 days if the goods are in stock. According to quantity your required, the delivery time may
slightlychange.

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